Article ID Journal Published Year Pages File Type
1417923 Carbon 2009 9 Pages PDF
Abstract

The influence of carboxylic multi-walled carbon nanotubes (c-MWCNTs) on the immune activities of dendritic cells (DCs), the most important professional antigen presenting cells, is evaluated. In spite of their diameters, c-MWCNTs are generously phagocytosed by DCs without any cytotoxicity. Treatment with c-MWCNTs, with concentrations of up to 100 μg/mL, does not induce phenotypical maturation of DCs. Furthermore, c-MWCNTs do not interfere with normal DC activation induced by stimulus, such as lipopolysaccharide. The results indicate that c-MWCNTs have good biocompatibility with DCs.

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