| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1425021 | Journal of Controlled Release | 2011 | 6 Pages |
Abstract
PNAs hybridized to the asialofetuin-oligonucleotide conjugates (AF/DNA) were internalized into hepatocytes effectively and were largely localized in the nuclei of the cells. More than 70% inhibition of telomerase activity was observed when PNAs complementary to the telomerase RNA template delivered to using AF/DNA.
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Authors
Tsutomu Ishihara, Arihiro Kano, Kentaro Obara, Minako Saito, Xuesi Chen, Tae Gwan Park, Toshihiro Akaike, Atsushi Maruyama,