| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1428888 | Materials Science and Engineering: C | 2013 | 5 Pages |
An ionic liquid–TiO2 nanoparticle modified carbon paste electrode (IL–TiO2/CPE) was used as a fast and sensitive tool for the investigation of the electrochemical oxidation of benserazide using voltammetry. This modified electrode has been fabricated using hydrophilic ionic liquid (n-hexyl-3-methylimidazolium hexafluoro phosphate) as a binder. The modified electrode offers a considerable improvement in voltammetric sensitivity toward benserazide, compared to the bare electrode. Using differential pulse voltammetry (DPV), the electrocatalytic oxidation peak current of benserazide shows a linear calibration curve in the range of 1.0–600 μmol L− 1 benserazide. The limit of detection was equal to 0.4 μmol L− 1. The relative standard deviation (RSD%) for eight successive assays of 10 μmol L− 1 benserazide was 1.1%. Finally, the proposed method was successfully applied to the determination of benserazide in real samples such as blood serum and urine.
Graphical abstractIn this study, we describe the application of a novel ionic liquid–TiO2 nanoparticle–paste electrode as a suitable voltammetric sensor for the determination of benserazide. The electrocatalytic oxidation peak current of benserazide shows a linear calibration curve in the range of 1.0–600 μmol L− 1 benserazide with a limit of detection equal to 0.4 μmol L− 1.Figure optionsDownload full-size imageDownload as PowerPoint slideHighlights► An ionic liquid–TiO2 nanoparticle modified carbon paste electrode was prepared. ► The modified electrode improved the voltammetric sensitivity of benserazide.► Benserazide could be measured in the range of 1.0–600 μmol L− 1.► Τhe sensor was applied to the determination of benserazide in real samples.
