Effect of iron-doped multi-walled carbon nanotubes on lipid model and cellular plasma membranes

The aim of the present work was the study of the interaction of multi-walled carbon nanotubes filled with iron (Fe-MWCNTs) with bimolecular lipid model membrane (BLM) and cellular plasma membrane (PM). The findings demonstrate that the Fe-MWCNTs adsorb on the BLM surface with possible partial build up in the hydrophobic area of fatty acid residues of lipids and increase its specific conductivity and capacity. Furthermore, upon interaction with the PM, the Fe-MWCNTs form channels which allow the flow of water to the cells and the externalization of phosphatidylserine from the inner to the outer PM leaflet.

Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Multi-walled carbon nanotubes filled with iron in water ► Interaction with bimolecular lipid model membrane and cellular plasma membrane ► Interaction leads to an increase of the specific conductivity and capacity. ► Carbon nanotubes are capable of forming channels in the membrane.