Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1429222 | Materials Science and Engineering: C | 2014 | 12 Pages |
•A Si-doped calcium phosphate coating was achieved via pulse ED on AZ31 alloy.•The coating was composed of a porous lamellar-like layer and outer block-like apatite.•The coating showed slow degradation rate and better biomineralization property.•The coating improved cell proliferation and activity of osteogenic marker ALP.
A silicon doped calcium phosphate coating was obtained successfully on AZ31 alloy substrate via pulse electrodeposition. A novel dual-layer structure was observed with a porous lamellar-like and outer block-like apatite layer. In vitro immersion tests were adopted in simulated body fluid within 28 days of immersion. Slow degradation rate obtained from weight loss was observed for the Si-doped Ca–P coating, which was also consistent with the results of electrochemical experiments showing an enhanced corrosion resistance for the coating. Further formation of an apatite-like layer on the surface after immersion proved better integrity and biomineralization performance of the coating. Biological characterization was carried out for viability, proliferation and differentiation of MG63 osteoblast-like cells. The coating showed a good cell growth and an enhanced cell proliferation. Moreover, an increased activity of osteogenic marker ALP was found. All the results demonstrated that the Si-doped calcium phosphate was perspective to be used as a coating for magnesium alloy implants to control the degradation rate and enhance the bioactivity, which would facilitate the rapidity of bone tissue repair.