Materials characterization and mechanobiology of the eye

The eye responds to a great deal of internal and external stimuli throughout its normal function. Due to this, a mechanical or chemical analysis alone is insufficient. A systematic materials characterization is needed. A mechanobiological approach is required for a full understanding of the unique properties and function of the eye. This review compiles the mechanical properties of select eye components, summarizes mechanical and chemical testing platforms, and overviews modeling approaches. Analysis is done across studies, experimental methods, and between species in order to summarize what is known about the mechanobiology of the eye. Several opportunities for future research are identified.

Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Critical aspects of the mechanobiology of the eye are reviewed. ► Materials characterization is emphasized. ► Important mechanical properties are compared. ► The review identifies several areas of opportunity for mechanobiology.