| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1430060 | Materials Science and Engineering: C | 2008 | 6 Pages |
Abstract
This communication reports that a plasmid DNA molecule could spontaneously interact with hydroxyapatite (HA) functionalized multi-walled carbon nanotubes (MWNTs-HA) in water-solute environment. Gel electrophoresis, UV absorption, FT-IR, and Raman spectra were used to characterize MWNTs-HA/DNA complexes. AFM and TEM images revealed that DNA induces the de-aggregation of MWNTs-HA. Our preliminary study suggests that the plasmid DNA significantly interacted with MWNTs-HA, and formed the stable complex, and could find the application in nanotechnology for gene delivery system.
Related Topics
Physical Sciences and Engineering
Materials Science
Biomaterials
Authors
Shanta Raj Bhattarai, Santosh Aryal, Remant Bahadur K.C., Narayan Bhattarai, Pyong Han Hwang, Ho Keun Yi, Hak Yong Kim,