Preparation and characterization of nanobiocomposites containing iron nanoparticles prepared from blood and coated with chitosan and gelatin

In this study, we report the preparation of magnetic iron nanoparticles (INPs) from goat blood using incineration method. FT-IR and XRD studies have confirmed that the prepared nanoparticles were INPs. These INPs were coated with a mixture of chitosan and gelatin to prepare INP–CG nanobiocomposite and the TEM picture of these composite particles has shown an average particle size of 80–300 nm. MRI scan exhibited magnetic property and VSM studies revealed a magnetic saturation of 18.97 emu/g. This may be used as a MRI contrast agent to enhance cellular imaging and as magnetic nanocarrier for targeted delivery of drugs in the diagnosis and treatment of cancer.

Graphical abstractINP's were prepared from blood and coated with chitosan and gelatin on their surface to form nanobiocomposites. This nanobiocomposite has exhibited magnetic property and a drop in signal was observed in MRI scan.Figure optionsDownload full-size imageDownload as PowerPoint slideResearch highlights► Raw materials used were obtained from natural source. ► Biodegradable. ► Can be tried as a MRI contrast agent. ► It may also find its application in targeted delivery for cancer treatment.