Synthesis of mesoporous hydroxyapatite using a modified hard-templating route

Mesoporous polycrystals of hydroxyapatite-calcium are synthesized via a modified hard-templating route. The structure properties of hydroxyapatite-calcium are characterized by means of X-ray diffraction, Fourier transform infrared spectroscopy, transmission electron microscopy and N2 adsorption–desorption isotherms. Wide-angle X-ray diffraction and Fourier transform infrared spectroscopy measurements reveal that the crystalline grains consist of highly crystalline pure hydroxyapatite phases. Transmission electron microscopy results show that rod-like hydroxyapatite-calcium grains with an average diameter of about 100 nm long and about 20 nm wide are uniformly distributed, which are also observed with an average pore size of 2–3 nm. Based on N2 adsorption–desorption isotherms investigation, the pore size, surface area and pore volume of mesoporous hydroxyapatite-calcium are 2.73 nm, 42.43 m2 g−1 and 0.12 cm3 g−1, respectively.