In vitro biological performance of minerals substituted hydroxyapatite coating by pulsed electrodeposition method

•We successfully achieved minerals substituted HAP coatings on Ti alloy by PED method.•The M-HAP coated Ti alloy exhibited better bioresistivity in SBF.•The as-coated sample showed antimicrobial activity and better cell viability.•The in vitro test displayed the formation of new cell growth.•The M-HAP coating can serve as a better candidate in orthopedic applications.

The present study deals with the optimization of minerals (Sr, Mg and Zn) substituted hydroxyapatite coatings (M-HAP) at different pulse on and off time (1 s, 2 s, 3 s and 4 s) by pulsed electrodeposition method. The formation of M-HAP coating was investigated using Fourier transform infrared spectroscopy (FT-IR) and X-ray diffraction studies (XRD). The morphological features and the content of Sr, Mg and Zn ions in M-HAP coated Ti–6Al–4V were investigated by high resolution scanning electron microscopy (HRSEM) and energy dispersive X-ray analysis (EDAX). The electrochemical studies were performed for M-HAP coated Ti–6Al–4V in simulated body fluid which exhibited better corrosion resistance at the prolonged pulse off time. The in vitro cell adhesion test revealed that the M-HAP coating is found appropriate for the formation of new cell growth which proves the enhanced biocompatible nature of the coating. Thus the M-HAP coating will serve as a potential candidate in orthopedic applications.

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