Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1527680 | Materials Chemistry and Physics | 2007 | 4 Pages |
Abstract
This study was conducted to predict the size-dependent melting temperatures of nanostructured griseofulvin (C17H17ClO6) and nifedipine (C17H18N2O6) drugs in their stable states embedded in polymer matrix based on a previous model for melting temperatures of nanocrystals. It is found that when the size of the drugs drops to several nanometers, the drops of the corresponding melting temperatures are more than 10%. Available experimental evidences support the model predictions.
Keywords
Related Topics
Physical Sciences and Engineering
Materials Science
Electronic, Optical and Magnetic Materials
Authors
X. Liu, P. Yang, Q. Jiang,