| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1539101 | Optics Communications | 2009 | 4 Pages |
Abstract
We present a new, sensitive, few mode fiber (FMF) surface plasmon resonance (SPR) biosensor with a sandwich assay for the detection of PSA. The side-polished FMF biosensor does not need a polarizer and a thin high-index overlayer. The optical sensitivity of the SPR sensor was determined as 2.5 × 10−6 RIU. In the SPR PSA sensor, the SPR signals were amplified by a factor of 6 in average over no secondary antibody, using the sandwich assay. The proposed FMF SPR biosensor has great potential for real-time analysis of immune reaction between biomolecules and the advantages of high-sensitivity and label-free detection.
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Authors
Hyun Soo Jang, Kwang No Park, Chang Duk Kang, Jun Pyo Kim, Sang Jun Sim, Kyung Shik Lee,