Effects of sleep deprivation on gamma oscillation of waking human EEG

This study compares and evaluates the effect of sleep deprivation (SD) on human brain cognition by analyzing the recorded EEG data under normal and 24 h sleep deprived states. EEG auditory event-related potentials were collected from 14 healthy volunteers, and the statistical values of wavelet-transformed EEG in gamma band were decomposed by parallel factor analysis (PARAFAC) to identify where the differences appeared in the time, frequency and spatial domains. The results showed that the changes of brain states caused by SD appeared around 40 Hz at about 400 ms after stimulation on prefrontal and frontal lobes. Negative effects of SD on neuronal activity and oscillation were observed. The analysis of the EEG data by the wavelet transform and PARAFAC can be an integrated way to estimate the change of brain states in the three domains.