Preparation and properties of nano-amorphous organic and inorganic particles via chemical and mechanochemical routes

Nanomization and amorphization methods of solid particles via energy and ecology conscious routes are overviewed. Particular emphasis was laid on the treatment of molecular crystals. Importance of autogenous process was introduced in conjunction with charge transfer across the boundary between dissimilar species, either in liquid or solid states. While nano-amorphization of molecular crystals is attainable by co-grinding, it is by no means rational, particularly when we need intensive milling for a long time. We therefore demonstrated to reduce grinding time to give just a small amount of liquid. The process was also compared with a novel sol–gel process without any mechanical stressing. Absorption of solvent or water vapor in the presence of hydrophilic polymeric matrix to obtain nano-amorphous particles, an entirely new process, was briefly referred.