Article ID Journal Published Year Pages File Type
1636092 Transactions of Nonferrous Metals Society of China 2013 7 Pages PDF
Abstract
The cytotoxicities of single-walled carbon nanotubes (SWNTs) and acid purified single-walled carbon nanotubes (SWNT-COOH) were investigated by spectroscopic analysis. Cell viability and cell apoptosis were applied to assessing the cytotoxicity of SWNT-COOH, cetyltrimethyl ammonium bromide (CTAB) and acid purified carbon nanotubes modified with cetyltrimethyl ammonium bromide (SWNT-COOH/CTAB). The results indicate that SWNTs are more toxic than SWNT-COOH. Concentration and time-curve analyses indicate that cytotoxicity of SWNT-COOH/CTAB is more related to the toxicity of the surfactant CTAB. The cytotoxicity effect of CTAB and SWNT-COOH/CTAB is acceptable at low concentrations (0.5-25 μg/mL). The cytotoxicity observation suggests that SWNT-COOH/CTAB can safely applied to biomedical field at low concentrations (0.5-25 μg/mL).
Related Topics
Physical Sciences and Engineering Materials Science Metals and Alloys
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