A novel in situ deposition of hydroxyapatite nanoplates using anodization/hydrothermal process onto magnesium alloy surface towards third generation biomaterials

•Anodization/HT process was performed on the AZ31B Mg alloy.•HA nanoplates like shape structure was generated after HT process.•An improved bioactivity and corrosion resistance of the alloy was resulted.•The generated nanoplates was found to mimic that in natural bone.

Third-generation biomaterials aim to stimulate specific cellular responses at the molecular level, these materials characterized with a resorbable and bioactivity that help body heal once they have been implanted. Here, a biomimetic method was used to generate hydroxyapatite (HA) nanoplates on the surface of AZ31B Mg alloy via anodization in simulated body fluid (SBF), followed by a hydrothermal (HT) process. The resulting nanoplates were characterized using FE-SEM, XRD, and FT-IR, surface hydrophobicity, in addition, corrosion was assessed electrochemically. The excellent bioactivity of the treated samples compared with naked ones were confirmed in vitro with MC3T3-E1 osteoblastic cells with significant growth and proliferation.

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