| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1642149 | Materials Letters | 2016 | 5 Pages |
•The decellularized pulp/collagen/fibronectin organized as fibril network.•The modified silk scaffold had effective biofunctionalities.•The modified silk scaffold promised for bone alveolar resorption.
A modified silk fibroin scaffold with mimic reconstructed extracellular matrix of decellularized pulp/collagen/fibronectin was proposed for bone tissue engineering in alveolar bone resorption. Silk fibroin scaffolds were fabricated by freeze-drying before modification by coating in a decellularized pulp/collagen/fibronectin solution. The extracellular matrix reconstruction of the decellularized pulp/collagen/fibronectin and the morphology and biofunctionalities of the modified scaffolds were evaluated. The results showed that decellularized pulp/collagen/fibronectin organized into a dense dendrite structure and adhered in the scaffold in a fibrillar network. The modified scaffold showed predominant biofunctionalities and promise for bone tissue engineering in alveolar bone resorption.
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