| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1644092 | Materials Letters | 2014 | 4 Pages |
Abstract
A novel poly(methacrylic acid) (PMAA) microcarriers coated with nanolayered chitosan(Cs) and carboxyl modified multi-walled carbon nanotubes (MWCNTs-COOH) via self-assembly method, has been successfully prepared for better loading and sustained release of gatifloxacin (GFLX). Due to the multi-loading and gradient release properties, PMAA/Cs/CNTs could adsorb a great amount of drug (84.89±9.63 μg mg−1), and 64.74±2.78% of its loading could slowly release in 24 h, which is important to delivery GFLX effectively and to reduce the risk of side effects.
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Related Topics
Physical Sciences and Engineering
Materials Science
Nanotechnology
Authors
Yunfeng Shi, Yeyun Fu, Hongling Lv, Jingxiang Zhong, Zonghua Liu, Dong Ma, Wei Xue,