Biocompatibility of electrospun graphene oxide–poly(ε-caprolactone) fibrous scaffolds with human cord blood mesenchymal stem cells derived skeletal myoblast

•Electrospun graphene oxide (GO)–poly(ε-caprolactone) (PCL) composite fibrous scaffolds prepared.•Biocompatibility of GO–PCL fibrous scaffolds studied.•Human cord blood mesenchymal stem cell derived myoblasts used for the biocompatibility study of the scaffolds.•First observation of myoblast adhesion and differentiation onto these GO–PCL scaffolds.

Biocompatibility of electrospun graphene oxide (GO)–poly (ε-caprolactone)-(PCL) composite fibrous scaffolds has been investigated using skeletal muscle cells obtained from human umbilical cord blood (UCB) derived mesenchymal stem cells (CB-hMSCs). Such CB-hMSCs derived human skeletal muscle cells (CB-hSkMCs) adhered, proliferated and formed myotubes when cultured on GO–PCL fibrous scaffold suitable for skeletal muscle tissue engineering applications.