Synthesis and characterization of periodic mesoporous organosilicas with uniform spherical core–shell structure used as a stationary phase

•New material with core–shell structure was synthesized and used as stationary phase.•New material combines the advantages of core–shell structure and PMOs.•New material showed high column efficiency and fast separation.•Rapid separation of aromatic compounds was achieved.

Micrometer-size periodic mesoporous organosilicas (PMOs) with a uniform spherical core–shell structure were prepared, and their application as a stationary phase for chromatographic separation was demonstrated in this study. The structure and morphology of this new material was characterized by Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM) and nitrogen sorption measurements. The results showed that the materials exhibited a spherical morphology, core–shell structure and mesostructure. This new material was tested as a potential stationary phase for HPLC because of its combination of a core–shell structure and PMOs. The new material showed high column efficiency for fast separation of aromatic hydrocarbon compounds.