Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1645763 | Materials Letters | 2013 | 4 Pages |
The aim of this study was to investigate into calcium phosphate (CaP) nucleation and growth on the electrospun nylon-6 nanofibers having its own and added functionalities of lactic acid (LA) and calcium lactate (CL) obtained by novel coating technique. LA was simply incorporated into the nylon-6 fibers by means of simple blending prior to electrospinning where as CL was deposited on the surface of as-formed core–shell structured fibers via simple acid–base neutralization. The bone formation ability of different functional groups on the fiber was evaluated by incubating in simulated body fluid. This study demonstrated a functionalities depended nucleation and growth mechanism of hollow CaP nanosphere on the surface of polymeric nanofibers.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Hollow CaP nanosphere were deposited on spider-wave-like nylon-6 nanonets. ► Functionalities depended mineralization of CaP was demonstrated. ► Core–shell structured nanofibrous mat was fabricated by single spinneret electrospinning.