Article ID Journal Published Year Pages File Type
1678106 Ultramicroscopy 2008 5 Pages PDF
Abstract

We report a new sample preparation method that allows the direct transmission electron microscopy evaluation of the architectural characteristics of biomolecules entrapped in gel matrices. We demonstrate that this sample preparation technique can be used for the identification and ultrastructural characterization of liposomes, collagen I and collagen III embedded in gel matrices, and has the potential to be useful for transmission electron microscopy (TEM) characterization of other biomolecule–gel matrix systems.

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Physical Sciences and Engineering Materials Science Nanotechnology
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