Article ID Journal Published Year Pages File Type
1682145 Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms 2012 6 Pages PDF
Abstract

Up to date, materials for cardiovascular stents are still far from satisfactory because of high risk of biomaterials-associated restenosis and thrombosis. Extensive efforts have been made to improve the biocompatibility of the materials by various surface modification techniques. Ti–O2−x films prepared by plasma immersion ion implantation and deposition (PIII&D) have shown good blood compatibility. For clinical application, surface quality and mechanical durability of the Ti–O2−x film on stents are also of critical importance for the long-term serving. In this paper we present our research results on surface quality, mechanical investigation and characterization of Ti–O2−x films prepared using PIII&D on stent products provided by Boston Scientific SCIMED. Ti–O2−x films with mostly Rutile and little non-stoichiometric phases were obtained with smoothness of <3 nm RMS, largely homogeneity as well as good intergradient film/substrate interface. The Ti–O2−x films on stents products were sustained balloon-expansion of clinically-required extent without mechanical failure, showing highly potential feasibility for cardiovascular stents application.

► We prepared Ti–O2−x films of good quality by PIII&D successfully on stents product. ► The Ti–O2−x film shows good homogeneity and intergradient film/substrate interface. ► The Ti–O2−x films on stent sustain clinically-required expansion without failure. ► The films show good mechanical durability for cardiovascular stents application.

Related Topics
Physical Sciences and Engineering Materials Science Surfaces, Coatings and Films
Authors
, , , , , ,