Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1682226 | Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms | 2012 | 11 Pages |
Technetium-99m, the daughter product of Molybdenum-99 is the most widely needed radionuclide for diagnostic studies in Pakistan. Molybdenum-99 Production Facility has been established at PINSTECH. Highly enriched uranium (93% 235U) U/Al alloy targets have been irradiated in Pakistan Research Reactor-1 (PARR-1) for the generation of fission Mo-99, while basic dissolution technique is used for separation of Mo-99 from target matrix activity. In line with the international objective of minimizing and eventually eliminating the use of HEU in civil commerce, national and international efforts have been underway to shift the production of medical isotopes from HEU to LEU (LEU; <20% 235U enrichment) targets. To achieve the equivalent amount of 99Mo with LEU targets, approximately 5 times uranium is needed. LEU aluminum uranium dispersion target has been developed, which may replace existing HEU aluminum/uranium alloy targets for production of 99Mo using basic dissolution technique. Neutronic and thermal hydraulic calculations were performed for safe irradiation of targets in the core of PARR-1.