| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1683520 | Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms | 2007 | 6 Pages |
Abstract
A technique has been implemented that could produce sub-micron resolution quantitative elemental mapping of cells in an acceptable time frame. A new experimental set-up was installed to produce 3D quantitative elemental maps of biological samples by combining simultaneous proton induced X-ray emission tomography (PIXE-T), on/off-axis scanning transmission ion microscopy tomography (STIM-T) and Rutherford backscattering spectrometry (RBS). Combined with a high efficiency Si(Li) detector, 3D quantitative maps of Cl, S, Ca, K, Fe and Zn in a section of a hair were produced with an analytical time of 3 h.
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Authors
Daniel Beasley, Nicholas M. Spyrou,