Chemical and radiological characterization of clay minerals used in pharmaceutics and cosmetics

Since the early days, clays have been used for therapeutic purposes. Nowadays, they are used as active ingredients or as excipient in formulations for a variety of purposes. Despite their wide use, little information is available in literature on their content of trace elements and radionuclides. The purpose of this study was to determine the elements (As, Ba, Br, Cs, Co, Cr, Eu, Fe, Hf, Hg, La, Lu, Rb, Sb, Sc, Sm, Ta, Tb, Yb, Zn, and Zr) and the radionuclides (238U, 232Th, 226Ra, 228Ra, 210Pb and 40K) in Brazilian clays as well as the health and radiological implications of the use of these clays in pharmaceutical formulations.

Research highlights► Determination of trace elements and radionuclides in Brazilian clay minerals. ► Health risk associated to the use of clay minerals in pharmaceutics and cosmetics. ► Radiological risk due to the use of clay minerals in pharmaceutics and cosmetics.