| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1696643 | Applied Clay Science | 2007 | 5 Pages |
Abstract
The present paper focused on the intercalation of ibuprofen (IBU) into montmorillonite as a sustained release drug carrier. The intercalation compounds were characterized by X-ray diffraction (XRD), Fourier transformed infrared (FT-IR), and thermogravimetric analysis (TGA). The basal spacing of montmorillonite increased from 1.25 nm to 1.57 nm. The decomposition temperature of intercalated IBU was increased to 471 °C. The in vitro release experiments revealed that IBU was released from MMT steadily and pH dependent.
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Authors
J.P. Zheng, L. Luan, H.Y. Wang, L.F. Xi, K.D. Yao,