Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
170414 | Comptes Rendus Chimie | 2013 | 7 Pages |
Abstract
A novel, simple, inexpensive and efficient ceric ammonium nitrate (CAN) catalysed one-pot, multi-component synthesis of 1,3-thiazine in PEG-400 has been developed. These derivatives were identified as potent inhibitor of Gram-negative bacteria and acted via inhibition of 4-diphosphocytidyl-2-Cmethyl-D-erythritol (IspE) kinase, a novel target.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Chemical Engineering (General)
Authors
Udaya Pratap Singh, Hans Raj Bhat, Ramendra Kumar Singh,