Article ID Journal Published Year Pages File Type
1704377 Applied Mathematical Modelling 2013 10 Pages PDF
Abstract

A virus dynamics model with Beddington–DeAngelis functional response and delays is introduced. By analyzing the characteristic equations, the local stability of an infection-free equilibrium and a chronic-infection equilibrium of the model is established. By using suitable Lyapunov functionals and the LaSalle invariance principle, we show that the infection-free equilibrium is globally asymptotically stable if R0⩽1R0⩽1 and the chronic-infection equilibrium is globally asymptotically stable if R0>1R0>1. Numerical simulations are also given to explain our results.

Related Topics
Physical Sciences and Engineering Engineering Computational Mechanics
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