Article ID Journal Published Year Pages File Type
1706272 Applied Mathematical Modelling 2011 9 Pages PDF
Abstract

In this paper, the dynamical behavior of a delayed viral infection model with immune impairment is studied. It is shown that if the basic reproductive number of the virus is less than one, then the uninfected equilibrium is globally asymptotically stable for both ODE and DDE model. And the effect of time delay on stabilities of the equilibria of the DDE model has been studied. By theoretical analysis and numerical simulations, we show that the immune impairment rate has no effect on the stability of the ODE model, while it has a dramatic effect on the infected equilibrium of the DDE model.

Related Topics
Physical Sciences and Engineering Engineering Computational Mechanics
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