Article ID Journal Published Year Pages File Type
170687 Comptes Rendus Chimie 2013 8 Pages PDF
Abstract

2-Hydroxyethylammonium acetate (2-HEAA) as a task-specific ionic liquid, efficiently promotes one-pot three-component reaction of aryl/heteroaryl/alkyl aldehydes with aryl/alkyl thiols and malononitrile at room temperature. This protocol offers several advantages such as using a reusable and cost-effective ionic liquid, being amenable to scale-up and produces the corresponding 2-amino-3,5-dicarbonitrile-6-thio-pyridines in a short reaction time (5 min) and in good to high yields.

Related Topics
Physical Sciences and Engineering Chemical Engineering Chemical Engineering (General)
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