Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
170788 | Comptes Rendus Chimie | 2012 | 5 Pages |
Abstract
Trifluoroethanol (TFE) is found to be an efficient and recyclable medium in promoting one-pot, three-component coupling reactions of isatoic anhydride, aldehyde and ammonium acetate or primary amine to afford the corresponding 2,3-dihydroquinazolin-4(1H)-one derivatives in high yields. The solvent (TFE) can be readily separated from reaction products and recovered in excellent purity for direct reuse.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Chemical Engineering (General)
Authors
Samad Khaksar, Saeed Mohammadzadeh Talesh,