Article ID Journal Published Year Pages File Type
1709223 Applied Mathematics Letters 2011 5 Pages PDF
Abstract

A class of virus dynamics model with intracellular delay and nonlinear infection rate of Beddington–DeAngelis functional response is analysed in this paper. By constructing suitable Lyapunov functionals and using LaSalle-type theorem for delay differential equations, we show that the global stability of the infection-free equilibrium and the infected equilibrium depends on the basic reproductive ratio R0R0, that is, the former is globally stable if R0≤1R0≤1 and so is the latter if R0>1R0>1. Our results extend the known results on delay virus dynamics considered in the other papers and suggest useful methods to control virus infection.

Related Topics
Physical Sciences and Engineering Engineering Computational Mechanics
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