Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
171227 | Comptes Rendus Chimie | 2011 | 8 Pages |
Abstract
2-Acetamido-1,4-imino-1,2,4-trideoxy-D-ribitol (DRBNAc) and the enantiomeric LRBNAc were prepared as potential hexosaminidase inhibitors from L- and D-lyxonolactone, respectively. Neither N-benzyl-DRBNAc nor N-benzyl-LRBNAc showed any inhibition of α- or β-hexosaminidases or any other glycosidase.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Chemical Engineering (General)
Authors
J.S. Shane Rountree, Terry D. Butters, Raymond A. Dwek, George W.J. Fleet,