| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 172165 | Computers & Chemical Engineering | 2015 | 8 Pages |
•Batch diafiltration process is studied in case of multi-component solution.•Optimal control structure derived analytically under several operational constraints.•Experimentally validated model is employed to illustrate the benefits.•Case studies show an improved performance using the optimal operation by up to 38%.
We study the minimum-time operation of batch multi-component diafiltration processes. We employ the technique of Pontryagin's minimum principle to derive the candidates for an optimal operation. The optimal operation is defined as a state-feedback strategy. Simulations and numerical optimizations are applied to confirm the optimality of the proposed time-optimal operation. Obtained results are evaluated on two case studies, a typical multi-component diafiltration processes. Standard operational approaches are compared to the optimal operation and the resulting improvements show attractivity of the proposed approach.
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