| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1722312 | Journal of Hydrodynamics, Ser. B | 2013 | 10 Pages |
The numerical simulation of the axial flow impeller blood pump NIVADIII is carried out by using a CFD multiphase flow model. The hydrodynamic performance of the pump and the flow field in the pump are analyzed, and the shear stress distribution is obtained. A hemolytic prediction model based on the shear stress is built based on the calculation results, and it can be used for qua- ntitative predictions of the hemolytic behavior of a blood pump. Hemolysis tests in vitro were performed 6 times with fresh bovine blood. At each time, the flow of the pump NIVADIII is 5 L/min and the outflow tract pressure is 100 mmHg. According to the tests, the plasma free hemoglobin (FHB) content and the hematocrit (HCT) are measured after 0 s, 0.5 s, 1 s, 1.5 s, …4 s. At the end of each experiment Normal Index of Hemolysis (NIH) of NIVADIII is calculated. The average of NIH is 0.0055 g/100L, almost identical with that obtained from the hemolytic prediction model. This method can be applied in the selection stage of a blood pump.
