Nuclear model calculations on the production of 119Sb via various nuclear reactions

Only very few radionuclides exist that decay exclusively by EC-mode without accompanying radiation, 119Sb is one of them. Auger emitter 119Sb (T1/2 = 38.9 h, IEC = 100%) is a potent nuclide for targeted radionuclide therapy based on theoretical dosimetry calculations at a subcellular scale. Auger electron emitting radionuclides in cancer therapy offer the opportunity to deliver a high radiation dose to the tumor cells with high radiotoxicity while minimizing toxicity to normal tissue.119Sb excitation function via 119Sn(p,n)119Sb, 120Sn(p,2n)119Sb, 121Sb(p,3n)119Te → 119Sb, 122Sn(p,4n)119Sb, 119Sn(d,2n)119Sb and 117Sn(α,2n)119Te → 119Sb reactions were calculated by ALICE/91, ALICE/ASH (GDH Model and Hybrid Model) and TALYS-1.0 (equilibrium and pre-equilibrium) codes. Requisite thicknesses of targets were obtained by SRIM code for each reaction.