A simulated annealing-based approach to the optimal synthesis of heat-integrated distillation sequences

A simulated annealing-based approach to synthesis of multi-component distillation systems is developed. An encoding procedure that makes use of an integer number series is developed to represent and manipulate the flow sheet structure of the system. With the representation procedure, the overall synthesis problem is formulated as an implicit mixed-integer nonlinear programming (MINLP) problem. A simulated annealing approach suitable for MINLP optimization is adopted and improved to solve the problem. Four example problems, including large-scale ones are solved to illustrate the approach.