| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 174647 | Current Opinion in Chemical Engineering | 2012 | 5 Pages |
Membrane crystallization (MCr) is an innovative concept related to the implementation of membrane technology in crystallization processes. Some important advantages make this methodology of growing interest: well-controlled nucleation and growth kinetics, fast crystallization rates and reduced induction time, membrane surface promoting heterogeneous nucleation, fine modulation of the level and rate of supersaturation, selection of polymorphic forms, extension of the MCr concept to antisolvent crystallization, and production of cocrystals.
► Membrane crystallization is a method for performing well-behaved crystallization processes. ► Supersaturation and the rate of its achievement can be regulated very precisely. ► Membrane surface operates as a physical substrate for heterogeneous nucleation. ► The membrane crystallization concept has been extended to antisolvent crystallization. ► The possibility to produce pharmaceutical cocrystals is a further attraction of the MCr technology.
