| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 175715 | Dyes and Pigments | 2015 | 7 Pages |
•Charge photosensitive drug can self-assemble by regulating environment ion strength.•Self-assemble degree can be controlled by ion strength.•Nanostructures with proper assemble degree have superior activity to monomers.
Self-assembled organic photosensitive nanoparticles have been widely used in diagnosis and therapeutic of cancer. In this manuscript, a simple but effective method to regulate the self-assemble degree of small charge photosensitive drug was demonstrated. Studies indicated that the ordered self-assembled nanostructures with proper assemble degree can significantly enhances the reactive oxygen species generation efficiency and, thereby, improve the in vitro photodynamic efficacy comparing with the corresponding monomers.
Graphical abstractA simple but effective method to regulate the self-assemble degree of small charge photosensitive drug was demonstrated to improve its photodynamic activity.Figure optionsDownload full-size imageDownload as PowerPoint slide
