Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1758901 | Ultrasonics | 2013 | 8 Pages |
Abstract
⺠To lower cavitation threshold, nucleation sites were generated on the interface of acoustic source and clot. ⺠The nucleation sites generated on the OD of a polyimide tube (PI) were either microfringed (MPI) or laser induced (LPI). ⺠Both MPI and LPI showed the potential of inducing cavitation in blood clots at acoustic pressure levels as low as 2.3 MPa. ⺠Cavitation enhanced thrombolysis rate by two times without any evidence of hemolysis. ⺠A transducer with nucleation sites on outer surface could be an intra-clot treatment option for acute ischemic stroke.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Acoustics and Ultrasonics
Authors
Azita Soltani,