Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1761484 | Ultrasound in Medicine & Biology | 2012 | 11 Pages |
Abstract
This study aimed to evaluate morphologic and tortuous features of vessels inside and outside the tumor region on three-dimensional power Doppler ultrasonography (PDUS) in 113 breast mass lesions, including 60 benign and 53 malignant tumors. Compared with benign lesions, malignant breast lesions had significantly larger values of vascular morphologic and tortuous features and larger tumor sizes. The receiver operating characteristic curve analysis and Student's t-test were used to estimate the performance of a proposed classification system using 13 vascular features and tumor size selected by the neural network. Accuracy, sensitivity, specificity, positive predictive value, negative predictive value and the AZ value of the diagnosis performance based on 14 features were 89.38% (101/113), 84.91% (45/53), 93.33% (56/60), 91.84% (45/49), 87.50% (56/64) and 0.9188, respectively. The three-dimensional PDUS morphologic and tortuous characteristics of blood vessels inside and outside breast mass lesions can be effectively used to classify benign and malignant tumors.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Acoustics and Ultrasonics
Authors
Yeun-Chung Chang, Yan-Hao Huang, Chiun-Sheng Huang, Ruey-Feng Chang,