Newtonian Viscous Effects in Ultrasonic Emboli Removal from Blood

We have modeled the removal of emboli from cardiopulmonary bypass circuits via acoustic radiation force. Unless removed, emboli can result in cognitive deficit for those undergoing heart surgery with the use of extracorporeal circuits. There are a variety of mathematical formulations in the literature describing acoustic radiation force, but a lingering question that remains is how important viscosity of the blood and/or embolus is to the process. We implemented both inviscid and viscous models for acoustic radiation force on a sphere immersed in a fluid. We found that for this specific application, the inviscid model seems to be sufficient for predicting acoustic force upon emboli when compared with the chosen viscous model. Thus, the much simpler inviscid model could be used to optimize experimental techniques for ultrasonic emboli removal.