Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1762870 | Ultrasound in Medicine & Biology | 2006 | 8 Pages |
Abstract
Flash-replenishment (FR) utilizes destruction of microbubbles in the scan volume by high-power ultrasound and enables to observe reperfusion at a low acoustic power. In this paper, we introduced theoretic equation between probability density function (PDF) of the transit time in the scan volume and time intensity curve (TIC) measured by FR method. From the equations, it was explained that the mean transit time (MTT) through the scan volume was calculated from the plateau level and tangent of the initial slope. Animal experiments were also performed to measure TIC in the parenchymal region of the liver using FR method. From the result of the TIC, the variant of the PDF for the transit time was found to be small and the average MTT was 11.1 s. Hepatic blood flow by an ultrasonic transit time flowmeter was also measured in the same experiment, and adequate correlation was obtained from between the two methods. The results suggested that the FR method, which is a noninvasive measurement, can predict the blood flow of the liver. (E-mail: moriyasu@tokyo-med.ac.jp)
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Acoustics and Ultrasonics
Authors
Ryo Metoki, Fuminori Moriyasu, Naohisa Kamiyama, Katsutoshi Sugimoto, Hiroko Iijima, Hui-xiong Xu, Takaya Aoki, Yuki Miyata, Kei Yamamoto, Kosei Kudo, Masafumi Shimizu, Masahiko Yamada,