| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 176467 | Dyes and Pigments | 2013 | 6 Pages |
Abstract
To enhance the solubility of two new photosensitizers (PS), obtained from natural products (Spirulina maxima and Rhodobacter sphaeroides), derivatization of purpurin-18 1 and bacteriopurpurin-18 3 with a cationic polymer: PEI (polyethylenimine) led to the production of polyaminated chlorins 5–6 and bacteriochlorins 7–8, respectively. These new water-soluble photosensitizers have been designed for their potential use in PDT: they are endowed with facilitated accumulation into cancer cells, and their respective Q bands, in the near-infrared region of the visible spectrum, span over the deepest therapeutic window of human tissues.
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Physical Sciences and Engineering
Chemical Engineering
Chemical Engineering (General)
Authors
Nicolas Drogat, Christelle Gady, Robert Granet, Vincent Sol,