Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1766708 | Advances in Space Research | 2011 | 5 Pages |
Abstract
In this study, we report an easy and quick method on simulating chromosome breaks in cells exposed to heavy charged particles. The theoretical value of chromosome break was calculated, and validated comparison with experimental value by using premature chromosome condensation technique. A good consistency was found between theoretical and experimental value. This suggested that higher relative biological effectiveness of heavy ions was closely correlated with its physical characteristics. Also, a safe approach on predicting chromosome breaks in cells exposed to heavy ions at off-line environment can be considered. Furthermore, three key factors influencing the theoretical simulation was investigated and discussed.
Related Topics
Physical Sciences and Engineering
Earth and Planetary Sciences
Space and Planetary Science
Authors
Qiang Wang, Gang Zhou, Xigang Jing, Wenjian Li, Jianshe Yang,