| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 176697 | Dyes and Pigments | 2013 | 5 Pages |
A fluorescent chemosensor N-n-butyl-3,4-diamino-1,8-naphthalimide (DAN) for detecting NO was developed on the basis of 1,8-naphthalimide with a similar structure of o-phenylenediamine as a NO reaction site. Due to the interaction between the photoinduced electron transfer (PET) and the intramolecular charge transfer (ICT), the chemosensor exhibits a remarkable enhancement in the emission intensity that is ca. 160-fold increase and a blue shift in the emission wavelength after the addition of NO. Meanwhile, it displays a colorimetric response accompanied with a color change from yellow to colorless. The chemosensor DAN shows a high selectivity for NO in the presence of various reactive nitrogen species (RNS) and reactive oxygen species (ROS). Furthermore, DAN can be used for bioimaging of NO in living cells.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► A fluorescent chemosensor for detecting nitric oxide (NO) was synthesized. ► The chemosensor was extremely sensitive to NO with about 160-fold fluorescence enhancement. ► It can rapidly and selectively detect NO in a colorometric way. ► The molecule can penetrate cell membrane easily and make fast fluorescence bioimaging.
