Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1767903 | Advances in Space Research | 2009 | 9 Pages |
Abstract
Although the available information is still not sufficient to decide whether the Linear No Threshold approach for low dose risk - including space radiation risk - has to be modified, these studies confirmed the need of a paradigm shift in (low-dose) radiobiology, where the DNA-centric vision needs to be integrated by a wider vision where cells constitute an organized population responding to external stimuli in a collective fashion, communicating by means of different molecular signals. Further studies, in particular in vivo (or at least in 3D tissues) and possibly combined with human epidemiological data, will be crucial to help solving such questions in the future.
Related Topics
Physical Sciences and Engineering
Earth and Planetary Sciences
Space and Planetary Science
Authors
Francesca Ballarini, Angelica Facoetti, Luca Mariotti, Rosanna Nano, Andrea Ottolenghi,