| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1802997 | Journal of Magnetism and Magnetic Materials | 2009 | 4 Pages |
Abstract
Immunomagnetic reduction (IMR), which involves measuring the reduction in the ac magnetic susceptibility of magnetic reagents, is due to the association between bio-functionalized magnetic nanoparticles and target bio-molecules. This has been demonstrated for assaying proteins in solutions free of Fe ions, such as serum. In this work, the validity of IMR assay for samples rich in Fe ions like hemoglobin (Hb) is investigated. According to the results, there is no magnetic signal contributed by Fe-ion-rich Hb. Furthermore, the results show a high sensitivity in assaying hemoglobin A1c (HbA1c) by using IMR.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Condensed Matter Physics
Authors
S.Y. Yang, C.B. Lan, C.H. Chen, H.E. Horng, Chin-Yih Hong, H.C. Yang, Y.K. Lai, Y.H. Lin, K.S. Teng,