Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1804191 | Journal of Magnetism and Magnetic Materials | 2007 | 4 Pages |
Abstract
Magnetic composite nanoparticles of gold and iron-oxide synthesized with gamma-rays or ultrasonics were functionalized with thiol-modified oligonucleotides. The amount of oligonucleotides bound to the functionalized nanoparticle probes via hybridization was quantified with fluorescently-labeled target oligonucleotides. Our composite nanoparticles magnetically separated the specific target oligonucleotides without the non-specific adsorption.
Related Topics
Physical Sciences and Engineering
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Condensed Matter Physics
Authors
Takuya Kinoshita, Satoshi Seino, Yoshiteru Mizukoshi, Takashi Nakagawa, Takao A. Yamamoto,